1. Finasteride is 4-azaandrost-1-ene-17-carboxamide, N-(1, 1-dimethylethyl)-3-oxo-,(5α, 17ß)-. The empirical formula of finasteride is C23H36N2O2 and its molecular weight is 372.55. Its architectural formula is.

    Finasteride is a white crystalline powder with a melting factor near 250 ° C. It is freely soluble in chloroform as well as in better alcoholic beverages solvents, yet is virtually insoluble in water.

    Proscar (finasteride) tablets for dental administration are film-coated tablets that contain 5 mg of finasteride and also the following non-active components: hydrous carbohydrate, microcrystalline cellulose, pregelatinized carbohydrate, sodium carbohydrate glycolate, hydroxypropyl cellulose LF, hydroxypropyl methylcellulose, titanium dioxide, magnesium mineral stearate, talc, docusate salt, FD&C Blue 2 aluminum lake and yellow iron oxide.

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    The advancement and enhancement of the prostate gland depends on the potent androgen, 5α-dihydrotestosterone (DHT). Type II 5α-reductase metabolizes testosterone to DHT in the prostate glandular, skin and liver. DHT induces androgenic results by expecteding to androgen receptors in the cell cores of these body organs.

    Finasteride is a affordable and specific prevention of Type II 5α-reductase with which it gradually develops a stable enzyme complex. Turn over from this complex is extremely sluggish (t 1/2 ~ 30 days). This has been demonstrated both in vivo and also artificial insemination. Finasteride has no fondness for the androgen receptor. In guy, the 5α-reduced anabolic steroid metabolites in blood as well as urine are lowered after administration of finasteride.

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